RS:
Is it a Nyle L200 you're getting?
Most folks, I'd guess, like to go with the biggest-sized chamber their unit can support (your Owner's info will clue you in if you don't already know your capabilities) and that's what I did the first time around back in the '90s. My unit was rated for 4MBF/load and that's what I always tried to give it. But I'm going a slightly different route this time.
In these parts, the only other (two) kiln operators have a pretty sketchy history of providing properly-dried lumber to their customers and, since I never seemed to have that problem (unhappy customers) in the past, I decided to dry smaller loads this time to minimize the possibilities of wet spots, mold, etc. I'm real happy with the results of my decision and, other than a little extra handling of the product, don't seem to have lost any volume at all while finding the quality of each and every board coming out of the unit to be acceptable. Not one problem with any of the degrade variables mentioned above.
My chamber allows for up to 1500BF/load, drying with a Nyle L200. I try to load only 10' lengths, 54" deep and about 6' high. The chamber is super-insulated and I ran the foil-faced foam on the inside of the chamber to allow for minimal surface friction on the airflow. Initial start-up temp is quickly attained and temp-control is a piece of cake. Venting is accomplished with adequate control and I'm delighted with the seeming minimal stress effected on the lighter load. We've run 5 loads (Red Oak, Cherry, Aspen) through in the last 6 weeks, all of which was in the 25%-30% MC range. I always "equalize" the lumber with the recommended 24-hours of fan time only, once the Compressor unit is shut down.
But my desires may well be fueled by different rationales. One thing that can't be denied is that air-flow sure seems to be maximized through a thinner stack of lumber, whether it's air-drying in the wind or having it forced through with fans. And that, to me, always means more efficient drying with less chance for problems of any type. I'm never afraid to poke a piece of my lumber for a customer with my probe-style MC meter when they ask for a random reading, either.
I'm sure you'll be seeing lots of good info provided within this forum. Have fun. It's just started!